Mechanism of action
The oral drug Valtrex contains a powerful antiviral agent Valacyclovir (500 mg or 1 g). This active component incorporates into the DNA of cells that are infected with the virus, and suppresses the process of their division and multiplication.
Valtrex has a high action selectivity against infected cells. At that, it is proven that it does not affect healthy cells and its antiviral effect is most pronounced at the initial stage of the infectious disease.
For the treatment of herpetic infections in adults, incl. the elderly, the drug is usedin high doses. Therefore, to quickly arrestherpes manifestations in adults, people usually buy Valtrex 1 g tablets.
People, who need to quickly buy Valtrex, can order the drug on online pharmacies. Some pharmacies provide a fact delivery of antiviral drugs. Therefore, visitors to online pharmacies can get Valtrex and start treatment for herpesvirus infection, when they notice manifestation of very first disease symptoms.
Patients, who start treatment within the shortest time after noticing any signs of the disease onset, notice the drug to help quickly stop the pathological process, stabilize their condition and reduce the clinical manifestations of herpes.
Severity of the herpetic infectionis usually assessed, when the dosing regimen is selected for diseases that are caused by the herpes simplex virus and varicella-zoster virus. Another important criteria for a proper dose selection is the patient’s age.
Adults and adolescents (12 y.o. and older), who go through the initial therapystage for fever blisters, are recommended taking a short course of Valtrex in a fairly high dosage. During a day:
- Adults should take two Valtrex 1 g tablets / twice a day
- Adolescents should take one Valtrex 1 g tablet / twice a day.
Valtrex dose of 1 g for primary genital herpesshould be taken for 10 days, twice a day. A shorter course (3 days) is required for the repeated genital herpes episodes, and implies the administration of two Valtrex 500mg tablets, twice a day.
To prevent the disease recurrence, patients with normal immunity take one Valtrex 500 mg tablet once a day. The daily dose for HIV-infected patients is two Valtrex 500mg tablets.
One-week treatment course with Valtrex is recommendedto treat herpes zoster. The overall daily dose of the drug during such course is 3 g. Patients should split it in 3 dosing events, and not take the entire dose at once.
The therapeutic dose for treating varicella in children aged 2 years and older is calculated based on the child’sbody weight. The total daily dose of Valtrex for the treatment of smallpox in a child should not exceed 20 mg per kg of body weight. The duration of the treatment course is usually 5 days.
Elderly patients do not need to adjust Valtrex dose, except in cases of impaired renal function. Since the risk of dehydration increases when metabolic processes slow down, it is recommendedto consume more fluids, while going through a Valtrexcourse.